Keywords

• Sugammadex sodium
• Sugammadex sodium supplier
• 343306-79-6

Quick Details

• ProName: best price Sugammadex sodium
• CasNo: 343306-79-6
• Molecular Formula: C72H104Na8O48S8
• Appearance: white powder
• Application: For pharmaceutical research
• DeliveryTime: Within 5 workdays after received the p...
• PackAge: as customer's requirements.
• Port: Tianjin,china
• ProductionCapacity: 500 Kilogram/Month
• Purity: 99.9%
• Storage: Kept in a cool, dry and ventilated pla...
• Transportation: air or sea
• LimitNum: 10 Gram

Superiority

Hebei Shengang Trading Co., Ltd is an experienced enterprise of supplier various kind pharmaceutical intermediates.

Our R&D center also offer custom synthesis services.

1.we have rich experience in this field.

2.we can provide competitive price for every customer and guarantee the quality of our goods.

3.we are attention to every customer's requirements and make a good relationship with them.

4.We have a long business relationship with many countries, such as Canada, Mexico, Brazil, United Kingdom, Russia, Germany, India, South Africa, Malta, Egypt, Armenia, Australia, Philippines, Belgium, Netherlands, Denmark ect.

if you have any other questions to consult me.please not hesitate to contact me at any time.

We just sell the products which are legal in china .And all products are only sold to labs for research.

Skype: freya698@163.com

QQ:3561179534

Mail:info@hbsgbiotech.com

Details

Sugammadex soidum is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA). Sugammadex is a modified γ-cyclodextrin, with a lipophilic core and a hydrophilic periphery. This gamma cyclodextrin has been modified from its natural state by placing eight carboxyl thio ether groups at the sixth carbon positions. These extensions extend the cavity size allowing greater encapsulation of the rocuronium molecule. These negatively charged extensions electrostatically bind to the quaternary nitrogen of the target as well as contribute to the aqueous nature of the cyclodextrin. Sugammadex's binding encapsulation of rocuronium is one of the strongest among cyclodextrins and their guest molecules. The rocuronium molecule (a modified steroid) bound within sugammadex's lipophilic core, is rendered unavailable to bind to the acetylcholine receptor at the neuromuscular junction.